Gaziantep is an important and industrial center in Turkey because of its pistachio nut plantations, olive groves and vineyards.
Aintap was an old city, located 12 kilometers north of the present city. It was continuously inhabited from the Paleolithic age and enjoyed periods of domination by a group of powers like Assyrians, Persians, Romans, Byzantines and Abbasids. The time during which Ottoman Empire rose also ruled Aintap. This era is characterized by many mosques, inns, baths and madrasas built in it.
In the village of Islahiye near Islahiye District, Yesemek Open Air Museum offers a step-by-step visual journey into sculpturing.
Rumkale is believed to date back to 840 BC and was built by the Hittites. Rumkale lived under rule from Assyrians, Medians, Persians, Romans and Arabs at various points in history. The remains of St. John are said to be spread throughout Rumkale during this area's different periods in history and it became a base for Christianity due to its importance as a fortress with many other relics dating back centuries.
The town of Karkamis in the Gaziantep region has a rich history. It started as an important center of trade during the antiquity when it was called Cerabulus and located on the Syrian border with only the citadel and inner town remaining in Turkey, and only the outer fortress and town remains in Syria.
The remains of the old city of Belkis (Zeugma) are located in Kavunlu village 10 kilometers away from Nizip district. On June 2005, the Gaziantep mosaic museum was opened and displays many pieces of unearthed mosaics and Mars statue from Zeugma.